With Its $10 Million Series A, Biobetter Brings Cultivated Meat Growth Media Down From $500,000 Per Gram to $1

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Israel-based cultivated meat startup Biobetter says it has closed a $10 million Series A funding round led by Jerusalem Venture Partners and additional investment from Milk and Honey Ventures, and the Israeli Innovation Authority.

Biobetter, which is using tobacco plants as bioreactors for its cell-based meat, says its novel tech has the potential to reduce the costs of cultured meat and help speed market entry.

Tobacco as a growth medium

“World population growth, combined with dwindling natural resources, are going to put incredible strain on meat supply—and the already fragile environment—in the coming decades,” Amit Yaari, PhD, CEO of Biobetter said in a statement. “Cultivated meat offers a promising solution to these problems and can ensure a more resilient supply chain with better economic and environmental returns.”

Tobacco plant testing
Tobacco plant testing, courtesy Biobetter

The company’s proprietary protein manufacturing platform levies tobacco in creating the growth factors the meat cells need to develop without the need for animal-based media. “The field-grown tobacco plants offer a new, sustainable, efficient, and flexible response to the market need for more competitively priced GFs, specifically insulin, transferrin, and FGF2. These compounds are necessary to make cultivated meat commercially viable,” the company said.

Typical growth medium costs can run between $50,000 to $500,000 per gram. But Biobetter says it can do it for one dollar per gram.

This, says Dana Yarden, MD, co-founder of Biobetter, is positioning tobacco for a “pivotal comeback as a catalyst for bringing better food security.” Yarden says the funding will allow BioBetter to scale up production in FY2023 and be market ready by 2024.

“Biobetter has the key to scale up production of cultivated meat, make it accessible to consumers globally and protect our planet,” said Erel Margalit, Founder & Executive Chairman of Jerusalem Venture Partners (JVP) and Margalit Startup City. “This is not only because of the sheer volumes of GFs it can produce but also by virtue of its ability to substantially reduce their cost.”

Israel’s alt-protein boom

“Biobetter has the potential to create global and regional impact,” said Nisan Zeevi, Director of JVP and VP of Margalit Startup City Galil.

“Closer to home, this venture will create a significant new source of income for local farmers. As cellular agricultural expands, we will dedicate some 500 acres here in the galilee of tobacco plantations to support the industry. This also helps growers find new purpose in the burgeoning alternative protein scene following a reduction in smoking over the last decade that has left many tobacco fields idle and tobacco farmers suffering financial loss.”

biobetter team
BioBetter Lands USD10M Funding to Relieve Cultivated Meat’s Bottleneck Using Tobacco Plants (Credit: Alexander Seleznyov)

Biobetter is part of the booming Israeli alternative protein sector. It is one of many food tech startups based out of Margalit Start-up City Galil, which is quickly becoming the country’s agri-tech hub.

A recent report from think tank The Good Food Institute Israel highlighted Israel’s success in the alt-protein space.

“2021 saw alternative protein placed at the forefront of [Israel’s] food-tech industry, with several massive investment rounds intended to accelerate scale-up and allow young companies to become global leaders for a better food system,” Aviv Oren, Director of Business Engagement and Innovation, GFI Israel, wrote in the group’s mid-year report.

“This momentum draws more investors, governments and multinational companies, as it is clearer than ever that to meet climate change goals and prevent future pandemics we must leverage technology to change the way we consume our food. Israel is leading this change, with more startups and more investment in alternative protein than any country besides the U.S.”

Photo of Dr. Amit Yaari, CEO and co-founder Biobetter, courtesy Alexander Seleznyov


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